2 PhD positions in translational oncology at the Medical University of Vienna
The Medical University of Vienna announces 2 PhD positions in the field of Translational Cancer Research, with a special focus on therapy resistance in cancer.
The overall scientific aim of the International PhD Program in Translational Oncology (IPPTO) is to better understand mechanisms shaping anticancer therapy responses, design strategies to better stratify patients, and to identify potential strategies that delay or impair therapy resistance.
Potential projects include (but are not limited to) :
Laboratory of Gergely Szakacs :
1) Contribution of genetic, phenotypic and clonal evolution to chemotherapy resistance. (2) Role of drug-tolerant persisters (DTP) in the evolution of therapy resistance.
Identification and experimental validation of targetable regulators of dormancy / survival or awakening of DTPs. (3) Role of TME in response to chemotherapy.
of Wolfgang Mikulits :
1) Study transforming growth factor-beta-dependent chemokine / cytokine networks in establishing metastatic traits of liver cancer and escaping from therapeutic treatments.
2) Investigate infiltration of neutrophils and lymphoid immune cells into the tumor microenvironment. (3) Examine the impact of epithelial plasticity on immune cell function and chemoresistance.